Move graph for participant selection. In this study, i measured the new urinary Na/K proportion and you may BP into the 12,890 people (84% off players was in fact off 2017) for a couple of decades. Fundamentally, 12,877 users was indeed examined
Na/K proportion
Tome Area requested members to gather the urine examples just after awakening am. The fresh new urinary Na/K ratio is mentioned using a beneficial urinary Na/K ratio-computing product named HEU-001F (OMRON Medical care Co., Ltd., Kyoto, Japan) (Additional Fig. 1). The display screen immediately details urinary Na/K ratio specifications. A public nursing assistant measured the fresh new Na/K ratio in the destination urine samples of the players playing with the computer, submitted the benefits, and offered immediate views into the professionals regarding your counted worthy of and explanatory procedure concerning dating amongst the urinary Na/K proportion and you will BP (Second Fig. 2). Tome Area performs wellness checkups into the for every single section from year to year out-of Can get so you can September. Ergo, members might have their urinary Na/K proportion mentioned meanwhile in 2017 and you will 2018.
Almost every other specifications
Information about most other specifications is actually obtained from the medical checkup research out of Tome City. One another pounds and the body height was basically mentioned within the fitness checkup. Body mass index are determined as the pounds (kg)/level dos (meters 2 ). BP is actually measured double from the an experienced societal wellness nursing assistant. chatfriends konum deÄŸiÅŸtirme Because fitness checkup data provided with Tome Town just integrated the lower BP dimension of these two BP dimension values, we can simply include this really worth in our studies. Blood pressure levels was defined as systolic BP (SBP) ? 140 mmHg or diastolic BP (DBP) ? ninety mmHg and/or perhaps the entry to antihypertensive medication. Information about liquor intake try received because of the a questionnaire. I calculated the newest alcoholic beverages consumption per week below: i multiplied the volume off alcohol based drinks (every single day = eight, often = step 3.5, no habitual taking = 0) and you will amount of alcohol used an individual affair (0–step one take in = 0.5, 1–dos beverages = 1.5, 2–step three products = dos.5, and step three drinks or higher = 3) and you can split up this product by eight. That take in within the The japanese represents 23 g regarding ethanol. Data on entry to diabetic issues cures and you may solution to cardiovascular system problem had been mind-claimed on fitness checkup research.
For information on using all forms of diabetes therapy, participants selected you to definitely alternative throughout the pursuing the solutions: (a) a track record of diabetic issues, (b) under treatment for diabetic issues mellitus, otherwise (c) the means to access diabetic issues cures. People that replied (c) have been classified because “users away from diabetes cures,” while people who replied having (a) or (b) or not appropriate had been categorized as the “anybody else.” Regarding details about the therapy for cardiovascular illnesses, players picked you to definitely choice regarding following solutions: (a) features a track record of heart problems otherwise (b) receiving treatment to own cardiovascular illnesses. People who answered (b) were classified just like the “receiving treatment having cardiovascular disease,” whereas people who responded which have (a) or perhaps not relevant was indeed classified as “someone else.”
Statistical study
To compare the difference between participants who attended health checkups both in 2017 and 2018 and those who attended health checkups only in 2017, we used the t-test for continuous variables and the chi-square test for categorical variables. For each year, we compared the baseline characteristics according to the urinary Na/K ratio level. Moreover, we analyzed the relationship between the urinary Na/K ratio and hypertension adjusted for age, sex, BMI, alcohol intake, use of diabetes medication, and treatment for heart disease. For longitudinal data, we assessed the relationship between change in urinary Na/K ratio and BP change using multiple regression analyses adjusted for age, sex, BMI change, and alcohol intake. In both cross-sectional and longitudinal analyses, we stratified the data according to the use of antihypertensive medication. We further added SBP or DBP in 2017 as a covariate. Furthermore, we analyzed the BP difference according to the urinary Na/K ratio quartile in 2017. To examine the effect of BP due to temperature, we acquired past temperature data from the Japan Meteorological Agency in 2017 and 2018 . We considered P < 0.05 as statistically significant.