I am not saying believing that the label faithfully shows the brand new contents of the brand new paper

Authors’ response

What is the method for determining prompt-evolving and you may sluggish-changing protein-coding genetics? In case the method is simply “Fool around with Ka”, I would personally argue that men and women have done one to ahead of.

Authors’ impulse

You will find altered this new name so you can “Nonsynonymous replacing rates (Ka) try a fairly consistent factor to possess defining timely-changing and you may slow-evolving protein-coding genetics”. I have featured the associated literary works very carefully and then have not discover products with over like comprehensive studies into the steps.

Recommendations

Lander Parece, Linton LM, Birren B, Nusbaum C, Zody MC, Baldwin J, Devon K, Dewar K, Doyle Yards, FitzHugh W, mais aussi al: First sequencing and you may data of your individual genome. Character. 2001, 409: 860-921. 7062.

Demuth JP, De Bie T, Stajich JE, Cristianini N, Hahn MW: The fresh new evolution away from mammalian gene family members. PLoS One to. 2006, 1: e85-/log.pone.0000085.

Williamson SH, Hubisz MJ, Clark AG, Payseur BA, Bustamante Cd, Nielsen Roentgen: Localizing latest adaptive advancement on individual genome. PLoS Genet. 2007, 3: e90-/log.pgen.0030090.

Bustamante Cd, Fledel-Alon A great, Williamson S, Nielsen Roentgen, Hubisz MT, Glanowski S, Tanenbaum DM, Light TJ, Sninsky JJ, Hernandez RD, Civello D, Adams MD, Cargill M, Clark AG: Natural possibilities on the necessary protein-coding genetics about human genome. Nature. 2005, 437: 1153-1157. /nature04240.

Nielsen Roentgen, Bustamante C, Clark AG, Glanowski S, Sackton TB, Hubisz MJ, Fledel-Alon An excellent, Tanenbaum DM, Civello D, White TJ, J Sninsky J, Adams MD, Cargill M: A scan having positively chose genes from the genomes out-of human beings and you can chimpanzees. PLoS Biol. 2005, 3: e170-/log.pbio.0030170.

Kosiol C, Vinar T, da Fonseca RR, Hubisz MJ, Bustamante Computer game, Nielsen R, Siepel A good: Patterns away from positive solutions inside half dozen Mammalian genomes. PLoS Genet. 2008, 4: e1000144-/journal.pgen.1000144.

Clark AG, Glanowski S, Nielsen R, Thomas PD, Kejariwal A good, Todd MA, Tanenbaum DM, Civello D, Lu F, Murphy B, Ferriera S, Wang G, Zheng X, Light TJ, Sninsky JJ, Adams MD, Cargill Yards: Inferring nonneutral evolution of individual-chimp-mouse orthologous gene trios. Technology. 2003, 302: 1960-1963. /research.1088821.

Locke DP, Hillier LW, Warren Lavatory, Worley KC, Nazareth LV, Muzny DM, Yang SP, Wang Z, Chinwalla At the, Minx P, et al: Relative and group investigation out-of orang-utan genomes. Character. 2011, 469: 529-533. /nature09687.

Gibbs RA, Rogers J, Katze Milligrams, Bumgarner Roentgen, Weinstock GM, Mardis Emergency room, Remington KA, Strausberg RL, Venter JC, Wilson RK, mais aussi al: Evolutionary and biomedical wisdom from the rhesus macaque genome. Science. 2007, 316: 222-234. /research.1139247.

Go CM, Giulotto Elizabeth, Sigurdsson S, Zoli Meters, Gnerre S, Imsland F, Lear TL, Adelson DL, Bailey E, Bellone RR, mais aussi al: Genome succession, relative studies, and you may population genes of one’s home-based horse. Technology. 2009, 326: 865-867. /research.1178158.

Lindblad-Toh K, Wade CM, Mikkelsen TS, Karlsson EK, Jaffe DB, Kamal Yards, Fasten M, Chang JL, Kulbokas EJ, Zody MC, et al: Genome sequence, comparative studies and haplotype structure of the domestic canine. Character. 2005, 438: 803-819. /nature04338.

Elsik CG, Tellam RL, Worley KC, Gibbs RA, Muzny DM, Weinstock GM, Adelson DL, Eichler EE, Elnitski L, Guigo R, mais aussi al: The genome sequence regarding taurine cattle: a screen to ruminant biology and you may evolution. Research. 2009, 324: 522-528. /science.1169588.

Waterston RH, Lindblad-Toh K, Birney E, Rogers J, Abril JF, Agarwal P, Agarwala R, Ainscough Roentgen, Alexandersson Meters, A keen P, mais aussi al: Very first sequencing and relative analysis of your own mouse genome. Characteristics. 2002, 420: 520-562. /nature01262.

Gibbs RA, Weinstock GM, Metzker ML, Muzny DM, Sodergren EJ, https://datingranking.net/hindu-dating/ Scherer S, Scott Grams, Steffen D, Worley KC, Burch PE, et al: Genome succession of your own Brownish Norway rodent returns skills to your mammalian evolution. Nature. 2004, 428: 493-521. /nature02426.

Mikkelsen TS, Wakefield MJ, Aken B, Amemiya CT, Chang JL, Duke S, Garber Yards, Gentles AJ, Goodstadt L, Heger An excellent, ainsi que al: Genome of one’s marsupial Monodelphis domestica reveals inside, 447: 167-177. /nature05805.