Kemi VE, Karkkainen MU, Karp HJ, Laitinen KA, Lamberg-Allardt CJ
Prices by the Ray Peat, PhD: “The new proportion out-of calcium in order to phosphate is very important; this is why dairy and you may cheddar are incredibly valuable for weight loss, or preventing gaining weight. For folks who aren’t most productive, reduced fat milk products and mozzarella cheese function better, because excess fat calories aren’t required.”
“The foods highest inside phosphate, according to calcium supplements, is grains, legumes, meat, and you will fish. Of many wishing dishes include additional phosphate. Edibles with a high, safe ratio away from calcium supplements to help you phosphate are leaves, such as for instance kale, turnip vegetables, and you may beet greens, and lots of fruits, milk products, and you will parmesan cheese.”
Br J Nutr
“Totally free unsaturated efas stimulate pressure hormonal, and cortisol stops oxidation of glucose and transforms they with the greasy acids and you may triglycerides. Remaining cortisol and fret reduced is the chief procedure. Staying a leading ratio of calcium supplements so you’re able to phosphate really helps to oppose the pressure kcalorie burning.” “Latest book try proving you to definitely continuously phosphate can increase inflammation, tissue atrophy, calcification of bloodstream, disease, dementia, and you can, in general, the fresh techniques from aging.”
2006 September;96(3):545-52. Large phosphorus consumption very and you can adversely connect with California and you will bone metabolic process into the a dose-oriented trend when you look at the healthy young lady. Kemi VE, Karkkainen best Italy gay dating app MU, Lamberg-Allardt CJ. California and you will P was both important nourishment to possess limbs and they are recognized to apply to one of the most important government of limbs k-calorie burning, parathyroid hormone (PTH). As well reasonable a P intake, typical of Western diet, might be deleterious in order to limbs from enhanced PTH hormonal. Partners managed amount-reaction scientific studies are on the effects out of highest P intake inside man. I studied the small-term results of five P dosage on the California and you can bones metabolic rate into the fourteen fit people, 20-twenty-eight years old, have been randomized to help you four managed data months; thus for each and every research topic supported because the her own handle. P enhance dosages out-of 0 (placebo), 250, 750 otherwise 1500 milligrams have been drawn, divided in to around three amounts inside analysis time. The meals served was in fact the exact same during for each investigation date and offered 495 mg P and you will 250 milligrams California. The P amounts impacted the newest serum PTH (S-PTH) inside the an amount-centered trends (P=0.0005). There’s a reduction in serum ionized California focus merely for the the highest P amount (P=0.004). The fresh marker of limbs creation, bone-particular alkaline phosphatase, reduced (P=0.05) plus the limbs resorption marker, N-critical telopeptide away from collagen kind of We, increased responding on P dosage (P=0.05). So it managed dose-reaction analysis showed that P possess a dosage-situated influence on S-PTH and you may develops PTH secretion significantly whenever California consumption is low. Exceptionally large P intake negatively impacts limbs k-calorie burning because of the coming down bones creation and you may increasing bone resorption, due to the fact conveyed because of the bone metabolism markers.
20 Oct 1. Increased calcium intake does not completely counteract the effects of increased phosphorus intake on bone: an acute dose-response study in healthy females. A high dietary P intake is suggested to have negative effects on bone through increased parathyroid hormone secretion, as high serum parathyroid hormone (S-PTH) concentration increases bone resorption. In many countries the P intake is 2- to 3-fold above dietary guidelines, whereas Ca intake is too low. This combination may not be optimal for bone health. In a previous controlled study, we found that dietary P dose-dependently increased S-PTH and bone resorption and decreased bone formation. The aim of the present study was to investigate the dose-response effects of Ca intake on Ca and bone metabolism with a dietary P intake higher than recommended. Each of the twelve healthy female subjects aged 21-40 years attended three 24-h study sessions, which were randomized with regard to a Ca dose of 0 (control day), 600 or 1200 mg, and each subject served as her own control. The meals on each study day provided 1850 mg P and 480 mg Ca. S-PTH concentration decreased (P < 0.001) and serum ionized Ca concentration increased (P < 0.001) with increasing Ca doses. The bone formation marker, serum bone-specific alkaline phosphatase, did not differ significantly (P = 0.4). By contrast, the bone resorption marker, urinary N-terminal telopeptide of collagen type I, decreased significantly with both Ca doses (P = 0.008). When P intake was above current recommendations, increased Ca intake was beneficial for bone, as indicated by decreased S-PTH concentration and bone resorption. However, not even a high Ca intake could affect bone formation when P intake was excessive.